Multiobjective Optimal Control of HIV Dynamics
نویسندگان
چکیده
منابع مشابه
Multiobjective Optimal Control of HIV Dynamics
Various aspects of the interaction of HIV with the human immune system can be modeled by a system of ordinary differential equations. This model is utilized, and a multiobjective optimal control problem MOOCP is proposed to maximize the CD4 T cells population and minimize both the viral load and drug costs. The weighted sum method is used, and continuous Pareto optimal solutions are derived by ...
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Recently, a couple of approaches have been developed that combine multiobjective optimization with direct discretization methods to approximate trajectories of optimal control problems, resulting in restricted optimization problems of high dimension. The solution set of a multiobjective optimization problem is called the Pareto set which consists of optimal compromise solutions. A common way to...
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In this paper, a computational approach is adopted for solving a multi-objective optimal control problem (MOOCP) formulation of optimal drug scheduling in human immunodeficiency (HIV) virus infected by individuals. The MOOCP, which uses a mathematical model of HIV infection, has some incompatible objectives. The objectives are maximizing the survival time of patients, the level of D...
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ژورنال
عنوان ژورنال: Mathematical Problems in Engineering
سال: 2010
ISSN: 1024-123X,1563-5147
DOI: 10.1155/2010/568315